Free US shipping over $50 90-day money-back guarantee 14,134+ five-star reviews
Doctor-designed nutrition · Since 1984

Built by doctors.
Refined for forty years.

MDR formulas are designed by physicians, dosed for real results, and trusted by tens of thousands of customers since 1984. No proprietary blends. No flashy marketing. Just nutrition that works.

  • 4.8 · 14,134+ reviews
  • 40 years · doctor-designed
  • 90-day · money-back guarantee
As featured in
The flagship lineup

Three formulas.
Forty years of results.

Start with one. Stack them as you grow. Every formula is a complete, doctor-designed system — not a single ingredient hiding behind a marketing claim.

Flagship
VitalFactors effervescent drink
Daily foundation · Anti-aging

VitalFactors

The original MDR formula. Restores NAD+, supports natural HGH, and rebuilds the cellular fuel your body quietly loses after 40.

4.8 · 14,134 reviews
$89/mo $99 one-time
Fitness Tabs for Men
Daily multivitamin · Men

Fitness Tabs for Men

Patented split-dose multivitamin. AM and PM tablets release the right nutrients at the right time of day for absorption and recovery.

4.91 · 2,340 reviews
$44/mo $49.95 one-time
Fitness Tabs for Women
Daily multivitamin · Women

Fitness Tabs for Women

Patented split-dose multivitamin. AM and PM tablets release the right nutrients at the right time of day for absorption and recovery.

4.82 · 3,108 reviews
$44/mo $49.95 one-time
Why MDR

What forty years of nutrition science looks like.

We don't ride trends. Every MDR formula is built on peer-reviewed research, designed by physicians, and dosed for the result — not the price point.

01

Doctor-designed

Formulated by physicians and nutrition scientists since 1984 — not by marketers chasing a category. Real doses, full-panel labels, no proprietary blends.

02

Forty years of formulation

The same families have trusted MDR for two and three generations. We've watched what works — and quietly retired what doesn't — for four decades.

03

90-day guarantee

Don't feel the difference in 90 days? Send back what's left. We refund the full purchase, shipping included, no form, no questions, no retention scripts.

The science

The two fuels your body
quietly loses after forty.

By midlife, NAD+ and human growth hormone fall sharply. That's why you feel slower, tire faster, and recover less. MDR's flagship VitalFactors helps restore both — and our broader catalog supports the rest of the system.

  • Clean cellular energy
  • Strength & muscle tone
  • Sharper focus
  • Cardiovascular support
  • Youthful skin
  • Libido & drive

1 Massudi et al., PLoS ONE 2012.   2 Corpas, Harman & Blackman, Endocr Rev 1993.

−0%
NAD+ by age 401
−0%
HGH by age 602
0+
customers feeling the shift
Why not just any supplement

MDR vs the supplement aisle.

What you'd find in a typical drugstore stack. What you get from a 40-year doctor-designed formulary.

MDR Nutrition Science Drugstore brands Typical category leaders
Designed by physicians Yes — every formula Usually marketers
Real, full doses Clinical-grade Often "fairy dusted"
Full ingredient transparency Every dose on the label Hidden in proprietary blends
Track record Forty years Often launched last quarter
Subscribe & save 10% off, free shipping Rarely
90-day money-back No form, no questions 30 days or none
Chris Cuomo

"Fitness and nutrition unite for a vibrant, healthy lifestyle. That's why I take VitalFactors as my favorite natural energizer."

The full catalog

Twelve more formulas for the rest of the system.

Bone & joint, heart, immunity, recovery, longevity. Every product designed in-house, dosed clinically, and backed by the same 90-day guarantee.

Energy · Immunity

Stress Defense Performance Tabs

Food-to-energy conversion, immune system, mental clarity, peak performance.

$29.95–$44.95 ★ 4.94
Bone & joint

Day-Cal

Calcium, magnesium, D3, K2, plus Resveratrol — bone & cardiovascular support.

$39.95 ★ 4.88
Joints

Chondro-Pro

Glucosamine, hyaluronic acid, antioxidants, FruitXB® Boron for joint comfort.

$34.95 ★ 5.00
Heart · Brain

Longevity Antioxidants

Boosts nitric oxide 230%. Antioxidants for circulation, heart, and brain function.

$49.95 ★ 5.00
Energy · Immunity

Mito-C

250mg Pureway-C® for natural energy, mitochondrial health, antioxidant defense.

$34.95 ★ 5.00
Topical · Pain

Roll-On Relief

Cooling-then-warming relief delivered exactly where you need it. Travel-friendly.

$19.95 ★ 5.00
Longevity

Ultra Pure Resveratrol

Active resVida® form. Heart, nerve, metabolism & the "longevity gene."

$29.95 ★ 5.00
Omega · Heart

Pristinium Antarctic Krill

Omega-3 phospholipids — 6,000× more antioxidant power than vitamin C.

$39.95–$69.95 ★ 5.00
Heart · Energy

Active CoQ10 Ubiquinol

The most absorbable form of CoQ10 — 4× the bioavailability of standard.

$49.95 ★ 5.00
Immunity

OnGuard Immune Defense

Natural compound stack engineered for everyday immune support.

$19.95–$69.95 ★ 5.00
Joints · Skin

Bio H.A. Firm & Flex

Krill oil + hyaluronic acid. Joint comfort and flexibility you can feel.

$29.95+ ★ 4.86
All products

Browse the full catalog →

Every formula, sorted by goal — energy, longevity, joints, brain, heart, skin.

15+ formulas Shop all
Real customers

People who moved the needle.

"I recommend MDR to my patients who want a clean, physician-designed stack — nothing flashy, just dosed correctly."

Dr. Russell Smith, MDEmergency Medicine

"My clients over 45 use VitalFactors to recover faster and hold their strength gains. It just works."

Nick MurthaOwner, Catalyst Fitness · Fort Lauderdale

"I've been performing for six decades. VitalFactors keeps me feeling like I've got another six in me."

Pat BooneSinger · Film Star

"Nothing hidden. The full panel is on the label and I can look up every ingredient. That's rare in this industry."

Sandra K.Verified subscriber · 2 years

"Ninety days later I feel the difference in my recovery and focus. The guarantee made it risk-free to try."

Marcus T.Verified subscriber · 14 months

"My mom got us all on Fitness Tabs years ago. I'm still on them. That's about as long-term as a supplement gets."

Janelle R.Verified subscriber · 6 years
Subscribe & save

Save 10%. Free shipping.
Cancel any time.

Most customers subscribe — it's cheaper per month, you never run out, and you can skip, pause, or cancel in one click from your account. No phone tree, no retention scripts.

Start a subscription
Questions

Before you start.

How quickly will I feel something?

Most customers report more consistent energy and better sleep within the first 2–3 weeks. Visible strength, skin, and endurance changes typically show up between weeks 6 and 12. Consistency matters more than dose — that's why VitalFactors is a daily drink rather than a capsule stack.

What's actually in MDR's formulas?

Every MDR product publishes its full Supplement Facts panel — no proprietary blends, no hidden doses. VitalFactors is built around precursors for NAD+, amino acids that support natural HGH, and a complete vitamin and mineral base. Fitness Tabs split a complete multivitamin into AM and PM doses for absorption and recovery.

Can I take this with my prescriptions?

MDR formulas are food-grade nutritional supplements, but any new supplement can interact with medications — especially blood thinners, blood pressure medication, and diabetes medication. Bring the Supplement Facts panel to your doctor before adding it. We'll honor the 90-day guarantee if your physician recommends you stop.

What's the subscription commitment?

Nothing beyond the current month. Skip a shipment, change the frequency, or cancel entirely from your account page in one click — or email us and we'll do it for you. No phone tree.

How does the 90-day guarantee work?

Try any MDR product for 90 days. If you don't feel a measurable difference, send what's left back and we'll refund your full purchase — shipping included. No form to fill, no questions required.

Is MDR evaluated by the FDA?

These statements have not been evaluated by the Food and Drug Administration. Our products are not intended to diagnose, treat, cure, or prevent any disease. We publish our sources so you can check the research yourself.

Start somewhere

Forty years of nutrition science,
one daily ritual at a time.

90-day money-back · Cancel anytime · Free US shipping over $50

Shop VitalFactors — $89/mo